# PhaseFolio

> Evidence, connected. PhaseFolio connects the public record of drug development, trial registries, regulatory decisions and company filings, into evidence that can be traced to its source. Every value in a comparison names the record and field it was read from and the date it was retrieved; assumptions, decisions, signed exports and every public figure are methodology-linked and version-stamped.

PhaseFolio has three products:

- **Atlas** compares trial records field by field, with every value linked to the registry record it came from. What a record does not report stays marked missing. Atlas surfaces cited source facts; it is not clinical decision support and does not rank efficacy across studies.
- **Workspace** keeps the evidence, assumptions, scenarios, decision records, audit history and signed export receipts behind a therapeutic investment case in one versioned record. Its rNPV model computes risk-adjusted valuations across the development lifecycle using BIO/QLS phase-transition benchmarks, indication- and modality-specific PoS, Monte Carlo simulation, and deal-structure modeling.
- **Sentinel** is in development to help teams follow changes across the programs and landscapes they care about. Monitoring and alerting are not yet available.

Public research pages, methodology pages, benchmark JSON, and signed-export verification are available without an account. Organization-scoped project, dossier, landscape, and evidence tools require authorization. The full list of public pages is in the [sitemap](https://phasefolio.com/sitemap.xml).

## Agent entry points

- [MCP server manifest](https://app.phasefolio.com/.well-known/mcp.json): Model Context Protocol endpoint at `https://app.phasefolio.com/api/mcp`. Public tools need no bearer token: `query_benchmarks`, `verify_export`, and `get_methodology`.
- [Open Knowledge Format index](https://phasefolio.com/okf/index.md): Google OKF-compliant bundle of structured methodology documents for AI agents.
- [REST OpenAPI specification](https://app.phasefolio.com/api/v1/openapi.json): machine-readable REST surface.
- [REST discovery index](https://app.phasefolio.com/api/v1): public API index with available endpoint families.
- [Development-stage literature benchmarks JSON](https://app.phasefolio.com/api/v1/benchmarks/development): peer-reviewed 2018-USD cost and elapsed-time estimates across 13 published therapeutic-area profiles plus the pooled All profile, with explicit PhaseFolio indication mappings and no pooled fallback for Rare Disease; display/reference only, not rNPV model inputs or PhaseFolio network benchmarks.
- [PoS benchmarks JSON](https://app.phasefolio.com/api/v1/benchmarks/pos): version-stamped phase-transition probabilities by indication and modality.
- [Network benchmarks JSON](https://app.phasefolio.com/api/v1/benchmarks/network): public preview of the anonymized benchmark data release.
- [Methodology JSON](https://app.phasefolio.com/api/v1/methodology): citation-grade methodology index.
- [Internal check records JSON](https://phasefolio.com/research/evaluations/verdicts.json): dated records of two internal checks (May 2026); not a validation of the model.

## Verify a PhaseFolio export

- [Verification portal](https://app.phasefolio.com/verify): paste an export hash to confirm authenticity and retrieve model, methodology, and benchmark versions.
- Verification API: `GET https://app.phasefolio.com/api/v1/verify/{hash}` verifies a signed dossier export by content hash.
- [Signing public key](https://app.phasefolio.com/.well-known/phasefolio-pubkey.pem): public key for independently checking signed PDF and Excel exports.

## Public methodology

- [Methodology hub](https://phasefolio.com/methodology)
- [Model card](https://phasefolio.com/methodology/model-card): what the model is for and not for, where every default comes from, its assumptions and its limits of use
- [rNPV model](https://phasefolio.com/methodology/rnpv)
- [PoS reference data and expanded modality normalization](https://phasefolio.com/methodology/pos-calibration): published baselines that prefill the asset modeler; every value is editable
- [Evidence standards](https://phasefolio.com/methodology/evidence-standards)
- [IRA terminal-value framework and modality class defaults](https://phasefolio.com/methodology/ira-framework)
- [Development path templates](https://phasefolio.com/methodology/development-paths)
- [Modelling deal terms](https://phasefolio.com/methodology/deal-term-modelling)
- [Holding valuation](https://phasefolio.com/methodology/holding-valuation): how held positions are valued, totals by basis and currency, and the look-through estimate's limits
- [Clinical stage normalization](https://phasefolio.com/methodology/stage-normalization)
- [COGS benchmark](https://phasefolio.com/methodology/cogs-benchmark)
- [SG&A benchmark](https://phasefolio.com/methodology/sga-benchmark)
- [Tax benchmark](https://phasefolio.com/methodology/tax-benchmark)
- [Methodology version history](https://phasefolio.com/methodology/changelog)

## Research

- [Research hub](https://phasefolio.com/research)
- [Internal checks](https://phasefolio.com/research/evaluations)
- [Internal check record](https://phasefolio.com/research/evaluations/signals)
- [Oncology signals internal check (May 2026)](https://phasefolio.com/research/evaluations/oncology-signals-2026)
- [Oncology signals full report, dated record](https://phasefolio.com/research/evaluations/oncology-signals-2026/report)

## Products and sources

- [Products](https://phasefolio.com/products)
- [Atlas](https://phasefolio.com/products/atlas)
- [Atlas release history](https://phasefolio.com/products/atlas/changelog)
- [Workspace](https://phasefolio.com/products/workspace)
- [Sentinel (in development)](https://phasefolio.com/products/sentinel)
- [Pricing](https://phasefolio.com/pricing): Atlas Free (no card, three datasets); Atlas Pro, Enterprise and Workspace by conversation.
- [Sources](https://phasefolio.com/sources): which public sources are live in Atlas, in beta, in development, or planned.
- [PoS benchmarks](https://phasefolio.com/benchmarks/pos)
- [Product documentation](https://docs.phasefolio.com/llms.txt)

## Support

- [Support](https://phasefolio.com/support)
- [Frequently asked questions](https://phasefolio.com/support/faq)
- [Troubleshooting](https://phasefolio.com/support/troubleshooting)

## Company and trust

- [About PhaseFolio](https://phasefolio.com/about)
- [Press](https://phasefolio.com/press)
- [Contact](https://phasefolio.com/contact)
- [Security and data handling](https://phasefolio.com/security)
- [Terms of service](https://phasefolio.com/terms)
- [Privacy policy](https://phasefolio.com/privacy)